A medical aesthetic treatment. Polynucleotide treatments inject a purified gel, often derived from salmon DNA, into the skin to support hydration and repair, and should be given by a trained medical practitioner. This page is general information, not medical advice. Suitability, results and risks vary between people. Always consult a qualified practitioner and confirm current details with the provider before booking.
Singapore is one of the most active markets in the world for polynucleotide skin treatments.
Polynucleotides, sometimes known by brand names such as Rejuran, are injectable skin treatments that aim to improve skin quality, hydration and elasticity over a course rather than adding volume like a filler. The ingredient is a purified gel often derived from salmon DNA that supports the skin's own repair processes. Singapore has a deep field of medical aesthetic clinics and dermatology practices that have offered this treatment since its rise in popularity from Korea, with many doctors experienced in the under eye area, acne scarring and overall skin quality. It is a course based treatment, usually a few sessions spaced weeks apart, with results that build gradually. Choose a registered doctor who assesses your skin honestly and explains what the treatment can and cannot do.
What to expect
On the day
After cleansing and numbing cream, the gel is injected as a series of small points across the area, often the face or under eyes, over twenty to forty minutes. A soothing mask and LED session may follow, so the full visit can take a couple of hours.
Downtime
Expect small bumps at the injection points, redness and the chance of bruising, especially under the eyes, settling over a few days. Many return to normal activities the same day while avoiding heat and strenuous exercise briefly.
How long it lasts
This is a course treatment, often two to four sessions spaced two to four weeks apart, with improvements building over weeks. Maintenance every several months is common. Results vary between people.
Real risks and downtime
Common and usually temporary effects include small bumps at the injection points, redness, swelling, tenderness and bruising, which can be more noticeable under the eyes. Less commonly there can be lumps, prolonged swelling or, rarely, infection at an injection site. Because the product is often derived from salmon, anyone with a relevant fish allergy should tell the doctor. It is generally avoided in pregnancy and breastfeeding, with active skin infection in the area, and with certain conditions. This is a newer treatment and individual responses differ, so results vary and are never guaranteed. A responsible doctor assesses suitability honestly and sets realistic expectations.
Singapore clinics worth knowing
A starting point, not a ranking. These are real, established Singapore practices. Confirm current practitioners, products and prices directly with each provider.
AEON Medical and Aesthetic Centre
A medical aesthetic centre offering polynucleotide skin rejuvenation as part of its injectable skin treatments. Confirm the treating doctor, suitability and current pricing with the clinic.
Radium Medical Aesthetics
A medical aesthetics clinic offering polynucleotide skin therapy aimed at skin quality and rejuvenation. Verify the practitioner, number of sessions advised and pricing directly with the clinic.
Lumine Dermatology and Laser Clinic
A dermatology and laser clinic offering polynucleotide skin booster injections. Confirm doctor availability, suitability for your skin and pricing with the practice.
Indicative Singapore pricing
A single session, varying by clinic, product and the area treated such as full face or under eyes.
Many clinics price a recommended course together. Sought after doctors and clinics can price higher.
These figures are indicative ranges and not quotes. Cost depends on the clinic, the specific product, the area and the number of sessions. As a course treatment, value lies in an experienced doctor and a realistic plan rather than the cheapest single session. Confirm current prices and course details with each clinic.
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