Both are injectables aimed at skin quality rather than volume, and both are often called biostimulators. They work in genuinely different ways, though, and they shine in different places. Here is an honest look at how to choose, and when a practitioner might combine them.
Profhilo is a stabilised hyaluronic acid placed at a few points, from which it spreads to deeply hydrate the skin and support collagen and elastin. Its strength is overall skin quality and mild laxity across areas such as the lower face, neck and hands. It is a bioremodelling treatment at heart.
Polynucleotides are regenerative injectables made from purified DNA fragments that act as repair signals, supporting the skin's own renewal and acting as an antioxidant. They are often chosen for finer, more delicate areas such as the under eye, and for skin that needs conditioning and resilience as much as hydration. Some clinicians use both in a plan, since their mechanisms complement each other.
Prices are indicative, gathered at build time and broad by design. Confirm current pricing, the exact product and the recommended number of sessions with the clinic. Prices vary and results vary.
These are medical aesthetic treatments. The information here is general and is not medical advice. Outcomes vary from person to person, results are never guaranteed, and every injectable treatment carries some risk. A qualified practitioner should assess your suitability in person and explain the risks before you proceed. Prices shown are indicative ranges only.
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