Beauty for Queens

By Fredrik Filipsson, Co-founder  ·  writes from first-hand patient experience  ·  Independent & not affiliated  ·  Last updated June 2026

PolynucleotidesCost guide

What polynucleotides cost

Pricing for polynucleotide treatment varies more than most injectables, because it is sold by the session and almost always done as a course. Here is an honest view of the ranges, what moves them, and why the lowest quote is rarely the smart buy.

Per session
£200 to £400

A typical single session for the face, indicative only.

Full course
£450 to £900

Two to three sessions, the usual starting protocol.

Under eye and premium
Higher end

Delicate areas and senior injectors sit above the range.

All figures are indicative ranges for guidance only. They vary by city, clinic, product and the number of areas. Always confirm the full course price with the provider before booking.

What moves the price

Five things to weigh

The product

Branded polynucleotides such as Plinest and Ameela carry different costs, and dedicated under eye formulations often cost more.

Number of sessions

A course is two to three sessions to start, then maintenance every six to nine months. Judge the course, not the single visit.

Areas treated

Face only is cheaper than face plus neck, hands or decolletage. More area means more product.

Who injects

A senior doctor or nurse with a strong safety record commands more than a junior, and for injections near the eyes that experience is worth paying for.

City and clinic

A central London or prime city address costs more than a regional clinic. Location is part of the price.

Value, not the cheapest

Why the lowest quote can cost more

Polynucleotides are an injectable, and the single biggest factor in a safe, satisfying result is the person holding the needle. A bargain price often reflects a less experienced injector, a rushed consultation, or under dosing that leaves you needing more sessions than quoted. The under eye area in particular is unforgiving. Spend your money on judgement and safety rather than the headline figure, and ask what the full course will total before you commit.

Good to know · Ask whether the quote is per session or for the full course, what product is used, and what a maintenance year would cost. A clear answer is itself a good sign.

Read next

The full polynucleotides guide

What it is and who it suits
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This is general information, not medical advice. Prices are indicative and results vary.

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